Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc2.4 | Look who is controlling your gonads! | ECE2018

Novel role of central ceramide signaling in mediating obesity-induced precocious puberty

Heras Violeta , Castellano Juan Manuel , Fernandois Daniela , Velasco Inmaculada , Roa Juan , Vazquez Maria J. , Ruiz-Pino Francisco , Pineda Rafael , Torres Encarnacion , Avendano Maria Soledad , Gaytan Francisco , Pinilla Leonor , Lopez Miguel , Casals Nuria , Tena-Sempere Manuel

Childhood obesity has become a major health problem, which is coupled to different adverse outcomes and diseases. The escalating prevalence of child obesity parallels that of alterations in pubertal timing, also linked to higher disease burden later on life. Yet, the mechanisms underlying for this association remain unfolded. Ceramides, ubiquitous signaling molecules involved in numerous biological processes, have emerged as mediators of metabolic disorders and transmitters fo...